England faces a big setback in Ashes series
He has been hit with a calf injury, the England and Wales Cricket Board announced Friday.
Anderson, England’s all-time leading wicket-taker, has not bowled in the series since breaking down with the injury after sending down just four overs in Australia’s 251-run win in the first Test at Edgbaston.
There had been hopes the 37-year-old Lancashire paceman would be fit for the fourth Test at his Old Trafford home ground starting on Wednesday. But after bowling during a second XI match against Durham this week he has been declared unfit for the final two Tests of the series.