The provincial police commandment said a clash broke out between the ISIS militants and the Afghan security forces in Chaparhar district late on Monday, leaving at least four ISIS militants dead or wounded.
The Nangarhar police officials are saying that the Afghan police and army forces were busy conducting routine patrol when they were ambushed by the ISIS militants.
The officials further added that the Afghan forces responded to the ISIS fire and forced the militants to retreat, leaving two of them dead.
According to the police officials citing intelligence reports two ISIS militants including Qari Habib the military commission in charge of the group were killed during the clashes.
The other ISIS member killed during the clashes has been identified as Qari Hanifa and two others were wounded, the officials said.
According to the security officials, the Afghan armed forces and the local residents did not suffer any casualties during the clashes.
The ISIS terrorist group has not commented regarding the clash and the killing of its senior leader so far.