She has visited an orphanage in Lahore on Saturday.
Bushra Bibi was accompanied by her friend, Farah Khan, during her first trip as first lady.
Thhe wife of PM Imran brought food for the children of the orphanage and will have lunch with them.
The prime minister's wife also said she will pay for the medical expenses of a child at the orphanage.
In her first message for the public on August 18, Bushra Bibi said she was more concerned than happy over Imran becoming prime minister.